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Statistical Inference and Modeling for High-throughput Experiments

Harvard University via edX

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Overview

In this course youll learn various statistics topics including multiple testing problem, error rates, error rate controlling procedures, false discovery rates, q-values and exploratory data analysis. We then introduce statistical modeling and how it is applied to high-throughput data. In particular, we will discuss parametric distributions, including binomial, exponential, and gamma, and describe maximum likelihood estimation. We provide several examples of how these concepts are applied in next generation sequencing and microarray data. Finally, we will discuss hierarchical models and...

Syllabus

Organizing high throughput data

Multiple comparison problem

  • Family Wide Error RatesFalse Discovery Rate
  • Error Rate Control procedures
  • Bonferroni Correction
  • q-values
  • Statistical Modeling
  • Hierarchical Models and the basics of Bayesian Statistics
  • Exploratory Data Analysis for High throughput data

Statistical Inference and Modeling for High-throughput Experiments
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Harvard University via edX

4 hours

$219.00 Certificate Available

English

On-Demand

Intermediate

Instructor

HarvardX

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